Friday, April 6, 2012

Dev Bio Exam 2 Notes

Part 1
Part 2

Notes from 3/16/12 (when I was sick, so these are neat notes courtesy of Angela Hsieh)

Part 3
Part 4

The scanner and I had a few more spats, so if you can't read anything, leave a comment or email/fbook me and I'll translate :D

****4/8/12 UPDATE
Edit to notes from 3/9/12:  nodal is expressed in LPM not "central plate mesoderm."

Edit to last diagram from 4/6/12: the yellow boxes or "sclerotome" split and rejoin, not the blue ovals of the myotome.

Edit to description of trunk NCCs from 3/14/12: trunk NCC migration in the dorsolateral direction is inhibited by both slit and ephrin.  At first glance, ephrin as a repulsor may seem counterintuitive since ephrin is a cell-cell adhesion molecule.  But as it turns out, ephrin to ephrin receptor binding can result in both adhesion and repulsion, depending on relative levels of expression of both molecules (the details of which are beyond of the scope of lecture).

Many thanks to Nadav Nahumi for pointing out these errors.  If anyone else spots some, please notify me.